Publications of the Aebi Lab

• PubMed Listing  »»

Latest publication

Schwarz F, Huang W, Li CS, Schulz BL, Lizak C, Palumbo A, Numao S, Neri D, Aebi M, Wang LX.
A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation.
Nature Chemical Biology, 6(4):264-266 April 2010.
[Abstract]

Recent publications:

N-Linked Protein Glycosylation in the Endoplasmic Reticulum

• Aebi M, Bernasconi R, Clerc S, Molinari M. N-glycan structures: recognition and processing in the ER. Trends in Biochemical Sciences 35(2):74-82 Feb. 2010.
  [Abstract]
• Izquierdo L, Schulz BL, Rodrigues JA, Güther ML, Procter JB, Barton GJ, Aebi M, Ferguson MA. Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases. EMBO Journal 28(17):2650-2661 Sep 2009. Epub 2009 Jul 23.
  [Abstract]
  
• Schulz BL, Stirnimann CU, Grimshaw JP, Brozzo MS, Fritsch F, Mohorko E, Capitani G, Glockshuber R, Grütter MG, Aebi M. Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc Natl Acad Sci U S A 106(27):11061-11066 Jul 2009. Epub 2009 Jun 23.
  [Abstract]
• Schulz BL, Aebi M. Analysis of glycosylation site occupancy reveals a role for Ost3p and Ost6p in site-specific N-glycosylation efficiency. Molecular & Cellular Proteomics 8(2):357-64 Feb 2009. Epub 2008 Oct 14.
  [Abstract]
• Clerc S, Hirsch C, Oggier DM, Deprez P, Jakob C, Sommer T, Aebi M. Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. Journal of Cell Biology 184(1):159-72 Feb 2009. Epub 2009 Jan 5.
  [Abstract]

Glycans and Lectins in Fungal Development

• Buser R, Lazar Z, Kaeser S, Kuenzler M, Aebi M. Identification, Characterization, and Biosynthesis of a Novel N-Glycan Modification in the Fruiting Body of the Basidiomycete Coprinopsis cinerea. Journal of Biological Chemistry 285(14):10715-10723 April 2010.
  [Abstract]
• Titz A, Butschi A, Henrissat A, Fan YY, Hennet T, Razzazi-Fazeli E, Hengartner MO, Wilson IBH, Kuenzler M, Aebi M. Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family.
  Journal of Biological Chemistry 284(52):36223-33 Dec 2009.
  [Abstract]
• Wälti MA, Walser PJ, Thores S, Grünler A, Bednar M, Künzler M, Aebi M. Structural basis for chitatetraose coordination by CGL3, a novel galectin-related protein from Coprinopsis cinerea. Journal of Molecular Biology 379(1):146-159 May 2008.
  [Abstract]

N-Linked Protein Glycosylation in Bacteria

• Ilg K, Endt K, Misselwitz B, Stecher B, Aebi M, Hardt WD. O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infection and Immunity 77(6):2568-2575 June 2009. Epub 2009 April 13.
  [Abstract]
  
• Slynko V, Schubert M, Numao S, Kowarik M, Aebi M, Allain FH. NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation. Journal of the  American Chemical Society 131(3):1274-1281 Jan 2009.
  [Abstract]
• Nasab FP, Schulz BL, Gamarro F, Parodi AJ, Aebi M. All in one: Leishmania major STT3 proteins substitute for the whole oligosaccharyltransferase complex in Saccharomyces cerevisiae. Molecular Biology of the Cell 19(9):3758-3768 Sep 2008. Epub 2008 Jul 2.
  [Abstract]