Institute of Microbiology

The Lanzavecchia Lab: Immune regulation

The aim of our current work is to unravel the basis of host resistance to infectious diseases to create a new generation of passive antibody therapies and vaccines. The human monoclonal antibodies that we isolate from memory B cells and plasma cells can be used not only as drugs for prophylaxis and treatment of infectious diseases, but also as tools to identify vaccine candidates. Besides these translational studies, we address fundamental issues with regard to the cellular basis of immunological memory, the role of somatic mutations in the generation of broadly neutralizing antibodies and the relationship between infection and autoimmunity.

Research Projects

Research Funding


Wichtiger Hinweis:
Diese Website wird in älteren Versionen von Netscape ohne graphische Elemente dargestellt. Die Funktionalität der Website ist aber trotzdem gewährleistet. Wenn Sie diese Website regelmässig benutzen, empfehlen wir Ihnen, auf Ihrem Computer einen aktuellen Browser zu installieren. Weitere Informationen finden Sie auf
folgender Seite.

Important Note:
The content in this site is accessible to any browser or Internet device, however, some graphics will display correctly only in the newer versions of Netscape. To get the most out of our site we suggest you upgrade to a newer browser.
More information

© 2015 Microbiology ETH Z├╝rich | Imprint | Disclaimer | 9 July 2014